Champions-elect Juventus scored twice in the closing stages to win the 186th Derby della Mole 2-0 at Torino.
After an all-Turin clash low on action and high on robust challenges, Arturo Vidal's wicked low drive from 20 yards broke the deadlock four minutes from time.
Torino had done well to keep a clean sheet until then, and had the occasional chance to find a winner of their own, but fell apart after going behind and soon had defender Kamil Glik dismissed for a second booking.
In stoppage time, Claudio Marchisio added an exclamation mark by converting substitute Fabio Quagliarella's headed assist from a set piece.
The win means a draw at home to Palermo will be enough for Antonio Conte's men to retain the Scudetto, while the neighbours are not quite sure of a second consecutive campaign in the top flight just yet.
Juan Cuadrado, Adem Ljajic and Alberto Aquilani shared the goals for Fiorentina who boosted their Champions League hopes with a 3-0 win at Sampdoria.
Inter Milan captain Javier Zanetti, 39, was carried off on a stretcher in the 17th minute of the 1-0 defeat at Palermo who boosted their hopes of avoiding the drop.
AS Roma forward Pablo Osvaldo produced the day's best individual effort with a hat-trick in the 4-0 defeat of next-to-bottom Siena.
Parma held Lazio to a 0-0 draw while Marco Borriello scored a potentially-crucial goal as Genoa beat Chievo 1-0 on the road to aid their survival efforts.
Colombian Cuadrado set Fiorentina on the way with a 30-metre effort in the 36th minute and Ljajic pounced on a poor clearance to score from just inside the penalty area five minutes later.
Siena's defeat at Roma sent them into the relegation zone, leaving them 19th in the 20-team table with 30 points, with Genoa and Palermo on 32 and Torino on 36. The bottom three go down.
Palermo are unbeaten in their last five games with Ilicic scoring in all of them. He struck in the 10th minute after dreadful Inter defending when Matias Silvestre was dispossessed in the area by Fabrizio Miccoli who laid off the ball for the Slovenian to score.
- Sports & Recreation
- Arturo Vidal
- Claudio Marchisio
- Fabio Quagliarella