The Argentine striker missed Inter's 3-1 defeat at Udinese last week due to a knee injury but manager Andrea Stramaccioni said on Friday that he was well again.
"Milito has recovered; he has a small problem with his knee that causes him a bit pain but isn't a serious medical problem," said the Inter coach at Friday's pre-match news conference.
Inter are fifth in Serie A on 35 points, nine behind leaders Juventus, after picking up one point in their last three games.
The 33-year-old Milito has scored eight goals in 18 appearances this season.
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