Kramer and Wust both led the men's and women's events heading to the final day with the former retaining his title and the latter returning to the top step of the podium for the first time since 2008.
Olympic 5000m champion Kramer had just the 10,000m to contest and ensured he took his sixth European title in seven years by comfortably winning it in 12:55.98.
Dutch team-mate Jan Blokhuijsen posted the second quickest time, 13:01.60, to leapfrog Havard Bokko and finish in the runner-up spot for the third Championships running.
Bokko fell to third overall, the second successive time he has occupied the last rung of the podium at the Europeans, after ranking fourth in the 10,000m in 13:08.16.
Double Olympic champion Wust meanwhile had two events to contest but took the overall win in similar style after being the quickest in the 1500m and second fastest in the 5000m.
Wust stated her intentions by posting 1:56.39 in the 1500m with Linda de Vries moving up to second overall after ranking second and Diane Valkenburg jumping to third after ranking third.
And that was how the top three was to remain, despite three-time defending champion Martina Sablikova of the Czech Republic being the only one to go under seven minutes in the 5000m.
Sablikova clocked 6:57.16 with Wust second quickest with 7:01.95 and de Vries third and Valkenburg fourth as the Czech skater finally relinquished her European title in Heerenveen.
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